Positive association of Apolipoprotein E4 polymorphism with recurrent pregnancy loss in Iranian patients
نویسندگان
چکیده
منابع مشابه
Association Of rs16260 Polymorphism Of CDH1 Gene With Recurrent Pregnancy Loss In Iranian-Azeri Women
Background & aim: Recurrent pregnancy loss is defined as loosing at least 2 pregnancies before 20th weeks of gestation. Besides all the known causative factors, in about half of the cases, the causing factor, remains unknown. In recent years, some studies have shown the role of candidate genes polymorphisms in RPL. CDH1 is one of these candidate genes that plays critical role in embryo implanta...
متن کاملP-193: The Association of Apolipoprotien E Polymorphisms with Recurrent Pregnancy Loss
Background: The role of apolipoprotien E polymorphisms do not diagnostic correctly in recurrent pregnancy loss etiology but Apo E has been shown to play an important role in lipid metabolism in pregnancy. We evaluated these polymorphisms in Iranian women with unexplained recurrent pregnancy loss. Materials and Methods: 5 ml Blood were sampling from 81 women with a history of two or more consecu...
متن کاملAssociation between Thrombophilic Gene Polymor-phisms and Recurrent Pregnancy Loss in Iranian Women
Background: Recurrent pregnancy loss (RPL) is a common problem among couples, and acquired thrombophilia is the well-known etiology of RPL. The aim of this study was to establish the association between inherited thrombophilic gene polymorphisms and RPL. Methods: This case-control study was conducted on 50 women with unexplained RPL and 50 parous women with no history of miscarriage (age range...
متن کاملAssociation study of CTLA-4 +49A/G gene polymorphism with recurrent pregnancy loss in the Iranian Azeri Turkish ethnic group.
BACKGROUND/AIM Recurrent pregnancy loss (RPL) is defined as two or more pregnancy losses. T-regulatory cells play an important role in the feto-maternal interface. Cytotoxic-T-lymphocyte antigen-4 (CTLA-4) is a molecule that downregulates the activation and proliferation of T cells. The objective of the current study was to investigate the possible association of CTLA-4+49A/G gene polymorphism ...
متن کاملAnalysis of Missense Mutations of CX3CR1 Gene in Patients with Recurrent Pregnancy Loss Using Bioinformatics Tools
Introduction: Abortion is a common complication that refers to the early termination of pregnancy with the death of the fetus before the 20th week of pregnancy. Previous studies show that many genes are involved in this disease, including the CX3CR1 gene, which is one of the inflammatory response genes in the immune system. The pathogenicity of these variants was determined in this study using ...
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ژورنال
عنوان ژورنال: Journal of Assisted Reproduction and Genetics
سال: 2013
ISSN: 1058-0468,1573-7330
DOI: 10.1007/s10815-012-9897-5